Radiobiology Unit

BIOLOGICAL DOSIMETRY LABORATORY

ÇNAEM Biodosimetry laboratory was established in 1988, provides routinely CA analysis to evaluate irradiated people or suspected of being over exposed with ionizing radiation and person who applied to get licenses for importing medical or industrial radiological instruments. It is well established dicentric and MN analysis techniques since 1988 and for FISH analysis since 1998. Standard procedures and methods are used according to IAEA technical Report No: 405.

ÇNAEM Biodosimetry laboratory only one serves to all of Turkey on assessment of ionizing radiation.

The dose is estimated by using of the observed yields of unstable chromosomal aberrations (Dicentrics and Centric rings) with standard dose response curve established in 1990 by our laboratory following in vitro irradiation of human lymphocytes for Co-60 gamma rays in a dose range of 0-5 Gy.

 

Figure 1: Possible Chromosome type Aberrations at irradiated human with ionizing radiation

 

Figure 2: Possible Chromosome type Aberrations at irradiated human with ionizing radiation  by FISH technique

 

Figure 3: Possible Alteration at human  nuclei caused by exposure to clastogenic and aneugenic agents